Creating protein affinity reagents on a proteome-wide scale is one of the greatest challenges of modern medicine. High quality reagents to capture proteins are necessary for elucidating protein function, developing new molecular diagnostics and even therapeutics. Recent advances in protein discovery will necessitate the need for affinity reagents to...

Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects about 1% of the world population and is characterized by synovial inflammation and joint destruction. Anti-citrullinated protein antibodies (ACPA) have been detected specifically in RA patients and may provide utility in RA risk assessment and diagnosis. ACPA levels correlate with...