Because the hip joint provides about 40-50 percent of the total average positive power for walking, injuries to this joint, or to the spine, can have a drastic impact on walking capabilities. Between total hip replacements, stroke, and other gait deteriorating injuries, there is already a significant population of patients with mobility deficits involving...

Very small implantable wireless telemetry systems have the potential to become a tool for continuous in vivo biomonitoring, implant monitoring and drug delivery. Such minimally invasive devices may provide a practical way of continuously monitoring of brain and central nervous system function, thusly enabling continuous physiological and biomarker monitoring...

Invention Description Type 1 diabetes (T1D) affects nearly 10 million people worldwide and occurs when the immune system destroys the pancreas's insulin-producing beta cells. Managing T1D is notoriously difficult, requiring constant glucose monitoring and precise insulin dosing. Even with advanced tools like continuous glucose monitors (CGMs) and...

Invention Description Monitoring cerebrospinal fluid flow in hydrocephalus patients is essential for ensuring proper valve function and preventing complications. Current monitoring methods are often invasive, intermittent, and unable to provide continuous real-time feedback on valve performance. Detecting valve malfunctions early can be difficult,...

Invention Description Accurately detecting stress using wearable devices is challenging due to significant differences in how individuals respond physiologically to stress. Variations in factors such as heart rate, skin conductance, and environmental conditions can reduce the reliability of stress detection models across different users. Many existing...

Invention Description Treating and monitoring deep brain regions is challenging due to the limitations of current neurotechnology, which often relies on invasive implants or inefficient transcranial methods. These approaches can involve surgical risks, bulky hardware, and limited precision in targeting specific neural pathways. Additionally, delivering...

Invention Description Diet profoundly impacts our nutritional landscape, public health, and disease susceptibility. In the gut, nutrients directly influence how intestinal stem cells (ISCs) function and maintain homeostasis. Yet, the connection between metabolic processes and transcriptional regulation are poorly defined. As a long-lived population,...

Invention Description Irritable bowel syndrome (IBS) is a prevalent and multifactorial gastrointestinal disorder that affects 10-15% of the US population. Because the pathophysiology of IBS remains poorly understood, current diagnostic tools and treatments are limited, with diagnosis often relying on symptom-based assessments and exclusion of other...

Invention Description Personalized human-sensing systems, especially in clinical and health applications, often struggle with limited user-specific data and significant variability between individuals. Differences in physiology, behavior, and environmental conditions can cause performance drops when models trained on general datasets are applied to...

Invention Description Orthopox monkeypox (MPXV) has recently emerged as a global viral threat with two distinct clades identified as endemic pathogens. It is estimated that 70% of the world’s population is vulnerable to infection by members of orthopoxviridae. Rapid identification of MPXV clades is critical, as Clade I infections are more clinically...