Invention Description Irritable bowel syndrome (IBS) is a prevalent and multifactorial gastrointestinal disorder that affects 10-15% of the US population. Because the pathophysiology of IBS remains poorly understood, current diagnostic tools and treatments are limited, with diagnosis often relying on symptom-based assessments and exclusion of other...

Invention Description Personalized human-sensing systems, especially in clinical and health applications, often struggle with limited user-specific data and significant variability between individuals. Differences in physiology, behavior, and environmental conditions can cause performance drops when models trained on general datasets are applied to...

Invention Description Orthopox monkeypox (MPXV) has recently emerged as a global viral threat with two distinct clades identified as endemic pathogens. It is estimated that 70% of the world’s population is vulnerable to infection by members of orthopoxviridae. Rapid identification of MPXV clades is critical, as Clade I infections are more clinically...

Invention Description Multimodal large language models (MLLMs) have shown strong potential in analyzing complex data types such as images, video, and audio, prompting growing interest in their use for medical applications. While several general-domain MLLMs have been adapted for healthcare tasks, including retinal imaging, their performance remains...

Two challenges facing the world today include the ongoing pollution of the environment with carbon dioxide and the increasing consumption of the world’s natural energy resources of fossil fuels. An elegant solution to these challenges would be to cultivate microorganisms such as algae that take and utilize carbon dioxide for their growth while...

Invention Description In the rapidly evolving field of live-cell analysis, recent innovations have enabled the sensing and quantification of specific intracellular nucleic acid targets, such as messenger RNA (mRNA) and other RNA species, in viable cells without requiring cell lysis or destruction of the sample. This capability is critical for drug...

Invention Description Antibiotic-resistant nontuberculous mycobacteria (NTM) infections are increasing at ~8% annually, placing a significant burden on healthcare systems. Mycobacterium abscessus (Mabs) represents one of the most treatment-refractory pathogens, particularly in cystic fibrosis (CF) patients. Mabs disease severity is strongly associated...

Invention Description Assessing honeybee worker populations is a critical index for monitoring colony health, productivity, and survivability in both agricultural and natural ecosystems. While essential for hive management, traditional population measurement techniques remain the industry standard despite being inherently labor-intensive and disruptive...

Invention Description Conducting learning-based models on large-scale unstructured geometric data, particularly volumetric 3D meshes, remains a significant challenge. While previous methods have employed graph convolutional approaches, they suffer from high space complexity, limiting efficient mini-batch training, as well as fixed short-range feature...

Invention Description Chronic and slow-healing wounds, particularly in diabetic and obese patients, pose a significant global, medical, and economic burden due to poor healing outcomes and limited effective treatments. Post-operative complications such as intestinal adhesions further complicate recovery and emphasize the need for targeted wound therapies. ...