More than 170 million people worldwide are chronic carriers of Hepatitis C Virus (HCV), but there is no therapeutic vaccine currently available for treating this infection. Persistent HCV infection results in chronic active hepatitis which may lead to progressive liver disease. Current treatment strategies are expensive, have substantial side effects,...

Noroviruses are hardy, highly contagious viruses that are the most common cause of acute gastroenteritis in humans. The CDC estimates that there are about 21 million illnesses caused by Noroviruses each year and about 800 of those result in death. There is no available vaccine for Norovirus infection and vaccine progress is hampered by the absence of...

Noroviruses (also known as Norwalk viruses) are believed to cause approximately 90% of epidemic nonbacterial outbreaks of gastroenteritis worldwide and may be responsible for 50% of all foodborne outbreaks of gastroenteritis in the US. The CDC estimates that up to 200,000 children under the age of 5 die of norovirus infection in developing countries...