Understanding the relationship between protein sequence-structure and binding dynamics is not well understood. Of particular interest is the ability to relate foldability and function of a protein and the ability to characterize how foldability and binding change based on mutations in the protein sequence. WW domains are one of the most abundant independently...

As technology scales, the number of cores in processors will rapidly increase in order to avoid the power wall. In processors that have hundreds and thousands of cores, traditional memory architectures – in which a coherent memory interface is provided to all the cores in hardware, will not be feasible. The memory management functionality is expected...