Gene delivery systems include both viral and non-viral carriers. The use of cationic polymers, such as aminoglycosides, as non-viral carriers has seen increased interest mainly due to their ease of synthesis, robust nature and gene delivery efficacies. Unfortunately, cationic polymers are also known for low gene expression and toxicity. Because of their...

Aminoglycoside antibiotics are known to prevent growth of gram-negative bacteria by inhibiting protein synthesis. Aminoglycosides possess biocompatible sugar groups as well as multiple amines in the same molecule. Their tenability and natural affinity towards nucleic acids makes them excellent candidates for generating diverse resins for multiple applications...