Invention Description Type 1 diabetes (T1D) affects nearly 10 million people worldwide and occurs when the immune system destroys the pancreas's insulin-producing beta cells. Managing T1D is notoriously difficult, requiring constant glucose monitoring and precise insulin dosing. Even with advanced tools like continuous glucose monitors (CGMs) and...

Invention Description Monitoring cerebrospinal fluid flow in hydrocephalus patients is essential for ensuring proper valve function and preventing complications. Current monitoring methods are often invasive, intermittent, and unable to provide continuous real-time feedback on valve performance. Detecting valve malfunctions early can be difficult,...

Invention Description Personalized human-sensing systems, especially in clinical and health applications, often struggle with limited user-specific data and significant variability between individuals. Differences in physiology, behavior, and environmental conditions can cause performance drops when models trained on general datasets are applied to...

Invention Description In the event of a terrorist attack or nuclear accident where large populations of individuals are exposed to radiation, it is critical for authorities to have the ability to quantify and confirm the levels of absorbed radiation. It is also essential for authorities to identify if an individual is exposed to greater than 2Gy where...

Invention Description In the rapidly evolving field of live-cell analysis, recent innovations have enabled the sensing and quantification of specific intracellular nucleic acid targets, such as messenger RNA (mRNA) and other RNA species, in viable cells without requiring cell lysis or destruction of the sample. This capability is critical for drug...

Invention Description Lyophilization is a critical process for stabilizing reagents in point-of-care (POC) diagnostics, effectively eliminating the need for cold chain storage and preventing liquid evaporation. While this technology is essential for developing robust field-deployable devices, current industry standards are limited to producing reagents...

Invention Description Rapid and reliable nucleic acid assays are critical for diagnosing infectious diseases at the point of need, yet most systems rely on complex, expensive instrumentation and trained personnel. These requirements limit access to timely diagnostics in low-resource, remote, or decentralized settings. Many platforms typically require...

Invention Description Wireless capacitive pressure sensors have been widely studied for health monitoring applications including continues monitoring of blood flow in patients suffering from high blood pressure, tracking of bladder pressure in patients with urine incontinence, and monitoring intracranial pressure in patients experiencing traumatic...

Invention Description Understanding of the pathobiology of Alzheimer’s disease (AD) has long been fragmented, with much research centered around biological mechanisms including amyloid β or tau proteins, inflammation, cell death pathways, glia, mitochondria and more. While these all deal with real facets in the biology of AD, they are limited...

Implementing liquid-based assays, such as PCR and LAMP, is difficult in POC microfluidic devices, due to bubble formation. To mitigate this, auxiliary metering systems or actuators are required to regulate consistent flow rates. This can make the microfluidic device more complicated to operate, increases cost, and limits rapid prototyping, ultimately...