Search Results - gene+expression

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  1. Identification of Biomarkers Towards Development of a Rapid Low-Cost Paper-Based Biodosimetry Triage Test
    Invention Description In the event of a terrorist attack or nuclear accident where large populations of individuals are exposed to radiation, it is critical for authorities to have the ability to quantify and confirm the levels of absorbed radiation. It is also essential for authorities to identify if an individual is exposed to greater than 2Gy where...
    Published: 2/26/2026
    Inventor(s): Joshua LaBaer, Vel Murugan, Jin Park, Madhuranga Thilakasiri Madugoda Ralalage Don
    Keywords(s): Biomarker discovery, Gene Expression, Machine Learning
    Category(s): Medical Diagnostics/Sensors
  2. System for Reversible Control of Morphotype Switching in Mycobacterium abscessus for Enhanced Disease Modeling and Therapeutic Research
    Invention Description Antibiotic-resistant nontuberculous mycobacteria (NTM) infections are increasing at ~8% annually, placing a significant burden on healthcare systems. Mycobacterium abscessus (Mabs) represents one of the most treatment-refractory pathogens, particularly in cystic fibrosis (CF) patients. Mabs disease severity is strongly associated...
    Published: 2/26/2026
    Inventor(s): Shelley Haydel, Rodrigo Aguilera Olvera, Lexi Yakimovich
    Keywords(s): Antibiotic Resistance Treatments, Antibiotic Resistant Bacteria, CRISPR-Cas, Gene Expression, Infectious Disease, Microbes, bacteria, fungi, virus, yeast, Microbiology, Mycobacteria, mycobacterial genetics, Pathogen
    Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Nucleic Acid/Peptide/Protein Therapies
  3. Single Cell In-Situ Extraction with Intact 3D Morphology from Formalin Fixed Paraffin Embedded (FFPE) Tissues
    FFPE is a well-established and widely used method for preservation and histological analysis of tissue samples. DNA/RNA/and Proteins can be extracted from FFPE samples, but generally lack single cell resolution and completely lack 3D spatial resolution. Enabling 3D resolution allows the correlation of morphology to information like gene expression,...
    Published: 2/13/2025
    Inventor(s): David Richardson, Thai Tran, Dmitry Derkach, Colleen Ziegler
    Keywords(s): Bioanalysis, Biological Cell Manipulation, Bio-Technology, Cancer, Device, Diagnostics, Gene Expression, Genomics, Proteomics, In situ, Molecular Diagnostics, Single-cell analysis
    Category(s): Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
  4. Biomarkers for Irritable Bowel Syndrome (IBS)
    Approximately 9% of the general population will report the onset of Irritable Bowel Syndrome (IBS) over a one year period. Unfortunately, at present, there is no standard and reliable diagnostic test for IBS. IBS is currently diagnosed using symptomatic criteria, but because symptoms of IBS can overlap with other GI diseases, there is considerable uncertainty...
    Published: 2/26/2026
    Inventor(s): Todd Sandrin, Peter Jurutka
    Keywords(s): Biosignature, Bio-Technology, Gene Expression, Genomics, Proteomics, MicroArray, Molecular Diagnostics
    Category(s): Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors

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