Search Results - antibiotic+resistance+treatments | Arizona Technology Enterprises

System for Reversible Control of Morphotype Switching in Mycobacterium abscessus for Enhanced Disease Modeling and Therapeutic Research

Invention Description Antibiotic-resistant nontuberculous mycobacteria (NTM) infections are increasing at ~8% annually, placing a significant burden on healthcare systems. Mycobacterium abscessus (Mabs) represents one of the most treatment-refractory pathogens, particularly in cystic fibrosis (CF) patients. Mabs disease severity is strongly associated...

Published: 2/26/2026

Inventor(s): Shelley Haydel, Rodrigo Aguilera Olvera, Lexi Yakimovich

Keywords(s): Antibiotic Resistance Treatments, Antibiotic Resistant Bacteria, CRISPR-Cas, Gene Expression, Infectious Disease, Microbes, bacteria, fungi, virus, yeast, Microbiology, Mycobacteria, mycobacterial genetics, Pathogen

Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Nucleic Acid/Peptide/Protein Therapies
Antibacterial Peptides, Synbodies, and Methods of Discovery

Antibiotic resistance is a worldwide clinical and public health problem, primarily stemming from the overuse of antibiotics. One of the most critical resistant pathogens is Methicillin-resistant Staphylococcus aureus (MRSA), which accounts for over 2,000,000 illnesses and 11,000 deaths each year. MRSA has developed resistance to all beta-lactam antibiotics....

Published: 2/26/2026

Inventor(s): Chris Diehnelt, Stephen Johnston, Pamela Hall

Keywords(s): Antibiotic Resistance Treatments, Antibiotic Resistant Bacteria, Antibiotics, Anti-Infectives, Drug Discovery, Infectious Disease, Peptides, Therapeutics

Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Proteomic Assays/Reagents/Tools, Pharmaceuticals, Vaccines/Antimicrobials