Studying single cells is difficult due to the laborious and costly cell isolation procedures which restrict throughput and impede the analysis of large numbers of cells or multiple samples in a single experiment. ASU researchers previously developed a method which used the cell’s membrane as a container for different reactions. One such reaction...

­Sequencing platforms have come a long way and are now capable of delivering enormous amounts of high-quality data, allowing for the possibility of sequencing the genomes of thousands of individual cells. Single-cell sequencing enables the examination of heterogeneity within populations and identifying rare or low frequency mutations that contribute...