Protein variants have been associated with many different and devastating human diseases including Alzheimer’s and Parkinson’s diseases, diabetes and cancer. Unfortunately, assessment of these protein variants is technologically difficult, primarily owing to two factors: a lack of binding partners that can distinguish between protein isoforms...

Microfluidic devices and systems have been used extensively for biological analyses driven in part by limitations in diagnostic methods, particularly the need for large sample volumes, extensive processing times, and low resolution and sensitivity. These devices are often highly portable and have been shown to work on a variety of diverse analytes including...