In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...

Many different graphic file formats are used for storing graphics: JPEG, TIF, GIF, etc. Highly desirable characteristic for all still digital image compression formats are quality and compression size. JPEG 2000 was developed as an open, ISO compliant technology that improved upon the JPEG file format. With the increased use in digital imaging technology...