Plants, algae and certain bacteria utilize photosynthesis to convert sunlight, water, and CO2 into oxygen and energy, which is the material basis for most biological activities on earth. However, their photosynthetic efficiency is low compared to theoretical values. Therefore, boosting this photosynthetic efficiency even a little above normal can translate...

Major histocompatibility complex class I (MHC-I) molecules are principal components of immune recognition. Peptide binding to MHC-I molecules is necessary for antigen presentation and T cell recognition. Understanding and predicting MHC-I binding has great utility in T cell therapies, vaccine development and treatment of complex human diseases. Unfortunately,...

T cell immunity is a fundamental component of the immune response to infections, cancer, and autoimmunity and is strongly impacted by polymorphisms in major histocompatibility complex (MHC) protein sequences. In particular, allelic MHC-I protein variants have been shown to influence patient outcomes to various viral infections, including SARS-CoV. While...