Accurate detection and diagnosis of infectious diseases is paramount to appropriate treatment and better outcomes. Despite tremendous efforts to advance new diagnostic techniques, there are still critical gaps in the healthcare system in quickly diagnosing and responding to infectious diseases. Current diagnostic technologies identify pathogens by detecting...

Accurate detection and diagnosis of infectious diseases is paramount to appropriate treatment and better outcomes. Despite tremendous efforts to advance new diagnostic techniques, there are still critical gaps in the healthcare system in quickly diagnosing and responding to infectious diseases. Current diagnostic technologies identify pathogens by detecting...

The ability to detect small molecules and other chemical analytes is important for many applications from assessing drinking water to monitoring effluents and ensuring food and drinks are safe to consume. While synthetic biology has enabled the development of molecular biosensors, such as transcription factors, to detect small molecules, they rely on...

­As we make our way through the third year of the global pandemic, one thing is abundantly clear, COVID testing is just as important now as it was in the beginning. But not all testing is created equal. PCR is highly sensitive; however, it requires well-trained personnel and expensive equipment, prohibiting home use and limiting use in areas with...

Because genetic information is used in pathogen detection, human genotyping, determining and detecting mutations which cause disease and for monitoring and treatment of infectious diseases, it is imperative that new methods for detecting nucleic acids are developed that are rapid, inexpensive and easy to implement. PCR-based methods for detecting nucleic...

Accurate detection and diagnosis of infectious diseases is paramount to appropriate treatment and better outcomes. Despite tremendous efforts to advance new diagnostic techniques, there are still critical gaps in the healthcare system in quickly diagnosing and responding to infectious diseases. Current diagnostic technologies identify pathogens by detecting...

Accurate detection and diagnosis of infectious diseases is paramount to appropriate treatment and better outcomes. Despite tremendous efforts to advance new diagnostic techniques, there are still critical gaps in the healthcare system in quickly diagnosing and responding to infectious diseases. Current diagnostic technologies identify pathogens by detecting...

Nonribosomal peptides are bioactive and highly diverse compounds, usually produced by microorganisms, which comprise some of the most important drugs in use today, including antimicrobials, immunosuppressants and anticancer compounds. These compounds are synthesized by nonribosomal peptide synthetases (NRPSs) which can incorporate over 300 different...

Noroviruses are the leading cause of gastroenteritis and foodborne illness, affecting millions and causing nearly $60 billion in societal costs each year. They are highly contagious and persist in the environment, resulting in frequent outbreaks in healthcare facilities, hospitals, schools and cruise ships. Further, these viruses can lead to severe...

Valley Fever (VF) or coccidioidomycosis is a systemic fungal infection that is endemic to the Southwestern United States with the highest frequency occurring in Arizona. Studies suggest that as few as 10 inhaled spores are sufficient to cause an infection. Of those who become infected, 40% experience flu-like symptoms or develop skin rashes, fatigue,...