­Molecular interactions in live cells play an important role in both cellular functions and drug discovery. Quantification of binding kinetics between drugs and cell membrane proteins is an essential step in drug evaluation. Current methods for measuring binding kinetics require the membrane protein to be extracted and labelled, both of which are...

­With the increase in evolution and resistance to multiple, commonly used antibiotics, bacterial infections are becoming an even greater public health concern. Urinary tract infections are particularly concerning given their high morbidity and high recurrence rates. Diagnosing bacterial infections relies on isolation and culture methodologies,...

Because of the misuse and overuse of broad-spectrum antibiotics, antimicrobial resistance has become a significant public health threat, causing billions of healthcare-related costs as well as millions of hospitalizations and 35,000 deaths annually in the US alone. Clinical treatment of bacterial infections, especially in cases of acute sepsis, includes...

Antibiotic resistance has become a significant public health threat, causing billions of healthcare-related costs as well as 2 million hospitalizations and 23,000 deaths annually in the US alone. Clinical treatment of bacterial infections, especially in acute cases of sepsis, requires multiple steps, including antibiotic susceptibility testing (AST)....