Optical characterization of cells and tissues is necessary to understanding physiological mechanisms. However, current optical imaging techniques have limited imaging depth, often because of strong optical scattering. Photoacoustic imaging (PAI) is a powerful technique which combines the high contrast of optical imaging with the high spatial resolution...

-collapse: collapse; } ­Volatile organic compounds (VOC) from different cell sources (cultured, animal or human) provide a wealth of untapped information regarding metabolic processes. They hold great potential for use as biomarkers for early non-invasive monitoring of cancer, infection and organ damage or failure. There are currently no technologies...

The activity of neurons has long been studied to characterize and understand neurological activity. Neurological activity is directly related to changes in membrane potential due to ion flux across the neuronal membrane. Imaging of this ion flux can provide insight into neural activity and enable research into function and disorders. Current approaches...

Ovarian cancer is the second most common gynecological malignancy in the United States and the most fatal. Although ovarian cancer treatments have advanced, approximately 85-90% of patients will experience recurrence with a median survival prognosis of only 12-24 months. While there are some indicators of disease recurrence they are detected with varying...