Search Results - antigen-specific+therapies

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  1. Reagents Targeting Neurodegenerative Diseases and Traumatic Brain Injury
    Misfolding and aggregation of proteins, such as beta-amyloid (Aß), alpha-synuclein (a-syn), tau and TAR DNA-binding protein 43 (TDP-43), have been strongly correlated with early onset of neurodegenerative diseases such as Alzheimer's Disease (AD), Parkinson's Disease (PD), Frontotemporal Dementia (FTD), amyotrophic lateral sclerosis (ALS) and...
    Published: 2/13/2025
    Inventor(s): Michael Sierks, Stephanie Williams
    Keywords(s): Antibodies, Antigen-specific Therapies, Bioassay, biomarker, ELISA, Mental Disorders, Traumatic Brain Injury
    Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Neurodegenerative Disease Technologies, Non-Cancer Therapeutics, Proteomic Assays/Reagents/Tools
  2. Recombinant Antibody Fragments that Selectively Target Oligomeric Tau Aggregates
    Alzheimer's disease (AD) is one of the most prevalent and feared neurodegenerative diseases associated with aging, characterized by progressive neuronal loss and cognitive dysfunction. AD affects nearly 5 million Americans, and unfortunately, there is no cure as of yet. Numerous studies have implicated oligomeric amyloid beta (Aß) aggregates as...
    Published: 2/13/2025
    Inventor(s): Michael Sierks, Huilai Tian, James Moe, Eliot Davidowitz
    Keywords(s): Antibodies, Antibody Therapeutics, Antigen-specific Therapies, Bioassay, Dementias, Diagnostics, Human aging, Protein, Therapeutics
    Category(s): Life Science (All LS Techs), Neurodegenerative Disease Technologies, Non-Cancer Therapeutics, Diagnostic Assays/Devices, Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
  3. High-throughput selection of pathogen specific antimicrobials from random sequence peptide microarrays
    Antimicrobial resistance is one of the biggest healthcare challenges. Overuse and misuse of conventional antibiotics along with their broad spectra have triggered development of multi-drug resistant superbugs. Researchers at Arizona State University have developed a novel process for producing alternative antimicrobial agents specific for any particular...
    Published: 2/13/2025
    Inventor(s): Valeriy Domenyuk, Chris Diehnelt, Stephen Johnston
    Keywords(s): Antigen-specific Therapies
    Category(s): Bioanalytical Assays, Chemistries & Devices, Proteomic Assays/Reagents/Tools, Vaccines/Antimicrobials, Life Science (All LS Techs)

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