Search Results - bioassay

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  1. Reagents Targeting Neurodegenerative Diseases and Traumatic Brain Injury
    Misfolding and aggregation of proteins, such as beta-amyloid (Aß), alpha-synuclein (a-syn), tau and TAR DNA-binding protein 43 (TDP-43), have been strongly correlated with early onset of neurodegenerative diseases such as Alzheimer's Disease (AD), Parkinson's Disease (PD), Frontotemporal Dementia (FTD), amyotrophic lateral sclerosis (ALS) and...
    Published: 2/13/2025
    Inventor(s): Michael Sierks, Stephanie Williams
    Keywords(s): Antibodies, Antigen-specific Therapies, Bioassay, biomarker, ELISA, Mental Disorders, Traumatic Brain Injury
    Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Neurodegenerative Disease Technologies, Non-Cancer Therapeutics, Proteomic Assays/Reagents/Tools
  2. Recombinant Antibody Fragments that Selectively Target Oligomeric Tau Aggregates
    Alzheimer's disease (AD) is one of the most prevalent and feared neurodegenerative diseases associated with aging, characterized by progressive neuronal loss and cognitive dysfunction. AD affects nearly 5 million Americans, and unfortunately, there is no cure as of yet. Numerous studies have implicated oligomeric amyloid beta (Aß) aggregates as...
    Published: 2/13/2025
    Inventor(s): Michael Sierks, Huilai Tian, James Moe, Eliot Davidowitz
    Keywords(s): Antibodies, Antibody Therapeutics, Antigen-specific Therapies, Bioassay, Dementias, Diagnostics, Human aging, Protein, Therapeutics
    Category(s): Life Science (All LS Techs), Neurodegenerative Disease Technologies, Non-Cancer Therapeutics, Diagnostic Assays/Devices, Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
  3. Noninvasive Tear Stress Sensors
    Chronic stress has been widely implicated in a plethora of lethal and life-altering diseases including diabetes, heart attacks, depression, Alzheimer's and osteoporosis. Thus, there is great interest in monitoring stress levels in the population. Stress has both biochemical and physiological effects on the body that can be quantified in bodily fluids....
    Published: 2/13/2025
    Inventor(s): Jeffrey LaBelle, Tina Hakimi, Brittney Cardinell
    Keywords(s): Antibodies, Bioanalysis, Bioassay, Cancer, Cardiovascular, Detection, Diabetes, Diagnostics, Health Monitoring, Sensors
    Category(s): Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Diagnostic Assays/Devices, Life Science (All LS Techs)
  4. Novel Antibodies for Detecting Gastric Cancer
    Gastric cancer (GC) is a major public health problem in many countries, with more than 1 million new cases, worldwide, in 2018, contributing to almost 800,000 deaths. And new research suggests that GC may be on the rise in the US, particularly among younger adults. Early detection of GC often allows for greater therapeutic options, however, because...
    Published: 2/13/2025
    Inventor(s): Joshua LaBaer, Ji Qiu, Lusheng Song, Yunro Chung
    Keywords(s): Antibodies, Antibody Therapeutics, Bioanalysis, Bioassay, Cancer, Diagnostics, Immunosignature, Infectious Disease, Protein Assays
    Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Medical Diagnostics/Sensors
  5. Microreactor Array Instrument/Platform
    High throughput parallel assays are needed to effectively identify and study biomolecules and their activity. Typically it takes a large number of repeated assays to get statistically significant data for studying biomolecules. However, fewer assays would be needed to get statistically meaningful results if the data were of higher quality. Because of...
    Published: 2/13/2025
    Inventor(s): Peter Wiktor
    Keywords(s): Array Techs - Micro, Nano, Gen,Proteomic, Bioassay, Bio-Technology, Detection, Diagnostics, Diffusion, DNA nanotechnology, Drug Discovery, Drug Screening, Drug Target Identification, ELISA, Genomics, Proteomics, Health Monitoring, High Throughput Sensors, Immunology, In situ, In Vitro, Instrumentation, Liquid Handling and Dispensing, MicroArray, Microbiology, Micro-Fluidics, Microreactor, Molecular Diagnostics, Nucleic Acid, Personalized medicine, Pharmaceutical, Polymerase Chain Reaction (PCR), Protein, Protein Assays
    Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Proteomic Assays/Reagents/Tools
  6. Aliquot Tray
    The design patents cover an ornamental design of an aliquot tray housing PCR tubes and caps set out in a regular spacing within the confines of a microwell plate. Each PCR tube can be removed on an individual bases without affecting neighboring tubes.The design ensures improved throughput, control and flexibility in reagent handling and storage. For...
    Published: 2/13/2025
    Inventor(s): Jeff Houkal, Jordan Yaron
    Keywords(s): Array Techs - Micro, Nano, Gen,Proteomic, Bioanalytical/Sample Reagents, Bioassay, Diagnostics, Liquid Handling and Dispensing, Medical Devices and Imaging, Polymerase Chain Reaction (PCR)
    Category(s): Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Proteomic Assays/Reagents/Tools
  7. Probes and Methods for Measuring Tandem Repeats
    Telomeres, tandem repeats at the ends of chromatids, are a particular point of interest in the science of aging and cancer. Telomeric DNA is lost during cellular replication, resulting in shortened chromatid length and cessation of cell division. Many age-related diseases are linked to shortened telomeres. Conversely, many cancer cells demonstrate elongated...
    Published: 2/13/2025
    Inventor(s): Fusheng Xiong, Wayne Frasch
    Keywords(s): Bioassay, biomarker, Cancer, Diagnostics, DNA nanotechnology, Early Detection, Molecular Diagnostics, Personalized medicine, PS-Bioengineering, Medical, Sensors, Singe molecule analysis, Telomerase
    Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools

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