The bleomycins (BLMs) are well-known antineoplastic agents, clinically useful in the treatment of squamous cell carcinomas and malignant lymphomas. The carbohydrate moiety, particularly the disaccharide moiety, of BLM is also known to be highly tumor targeting. Researchers at the Biodesign Institute of Arizona State University have discovered disaccharides...

The bleomycins (BLMs) are well-known antineoplastic agents, clinically useful in the treatment of squamous cell carcinomas and malignant lymphomas. The carbohydrate moiety of BLM is also known to be highly tumor targeting. Methotrexate is a highly effective antitumor agent as well and is used to treat cancers of the skin, head and neck, lung and breast....

There is tremendous diversity in the structure and function of peptides and proteins, thus peptide and protein engineering is an area of intense interest. There are many means to accomplish peptide and protein engineering, but the overarching goal is to design and engineer the chemical structure to improve the molecular properties and achieve increased...