Many early stage cancers have a high rate of survival if promptly diagnosed and treated. Survival rates for stage 1-3 breast cancer can be as high as 95% at the 5 year mark. Unfortunately, late stage cancers have a much lower survival rate; stage 4 breast cancer only has about a 20% survival rate at the 5 year mark. Metastatic cancers pose a particularly...

The bleomycins (BLMs) are well-known antineoplastic agents, clinically useful in the treatment of squamous cell carcinomas and malignant lymphomas. The carbohydrate moiety of BLM is also known to be highly tumor targeting. Methotrexate is a highly effective antitumor agent as well and is used to treat cancers of the skin, head and neck, lung and breast....

Current neural interface and neuromodulation technologies lack the stability and specificity to target specific sensory or motor neurons within a nerve bundle. Emerging prosthetic devices for the central and peripheral nervous system require interfaces that can stimulate or sense targeted neurons with high discriminability to achieve very specific end-target...