Recombinant protein subunit vaccines offer an improved safety profile compared to live attenuated or inactivated vaccines, making them a promising vaccine strategy. These vaccines can further enhance immunogenicity through fusion with IgG-based protein scaffolds, such as immune complex (RIC) platforms. RIC consists of an antibody and antigen complex...

Vaccines are an essential tool in preventing and controlling many diseases. Most approved vaccines are inactivated or live attenuated type, however, alternative platforms like mRNA and virus-like particles (VLPs) are being increasingly explored and approved because they generate potent immune responses with great safety profiles. VLPs are particularly...

Cyanobacteria are model species for studying photosynthesis and recently have been gaining increased attention for their ability to produce renewable fuels and chemicals by harvesting solar energy and recycling carbon dioxide. Unfortunately, despite all the recent research and exciting achievements made regarding cyanobacteria, genetic transformation...

Plants are a promising platform for rapid production of biologics as they offer many advantages over traditional systems, including safety, speed, versatility and cost. Geminiviruses are a group of small plant viruses that have been studied and used extensively in such plant-based production systems. Because geminiviruses replicate in nuclei, their...

Gene delivery systems include both viral and non-viral carriers. The use of cationic polymers, such as aminoglycosides, as non-viral carriers has seen increased interest mainly due to their ease of synthesis, robust nature and gene delivery efficacies. Unfortunately, cationic polymers are also known for low gene expression and toxicity. Because of their...

Live recombinant attenuated Salmonella-vectored vaccines hold great promise as a means to improve human health by generating long-lasting mucosal, humoral and cellular immunity against Salmonella and a variety of non-Salmonella pathogens at a low cost. Salmonella Typhimurium elicits a robust host immune response by targeting M cells present on the luminal...

Plants are a promising platform for rapid production of biologics as they offer many advantages over traditional systems, including safety, speed, versatility and cost. And the demonstration of plant-made pharmaceuticals that have been glycoengineered to have authentic human N-glycans further underscores their promising potential. However, high accumulation...

The market interest in bioproduction of chemicals and polymers is steadily growing, driven by sustainability concerns and increashttp://azte.technologypublisher.com/files/sites/ncs-m12-182,-m14-208l,-m14-232l.pdfed environmental awareness. However, most production technologies rely on petroleum or food crops as feedstocks. In the coming decades, materials...

Despite the success of antiretroviral treatments, there are still millions of new cases of human immunodeficiency virus (HIV) every year, with a higher prevalence in areas of the world with limited healthcare access. Vaccine strategies have been extensively studied and even developed to try to prevent or limit the spread of the virus. Current vaccination...

2-Phenylethanol is a naturally-occurring aromatic alcohol and key molecule used in the flavor and fragrance industries due to its floral, rose-like aroma. Additionally, 2PE has been considered as a potential biofuel or fuel additive due to its low volatility, high energy density and non-hygroscopic properties. Natural 2PE can be obtained from various...