Fresh fruits and vegetables (FVs) can cause foodborne diseases as they are able to harbor a variety of human pathogens and parasites. The short shelf life of fresh produce, due in large part to microbial induced spoilage, is a serious problem that costs the food industry billions a year. Further, nutrients, polyphenols and other bioactive compounds...

SDS-PAGE is a ubiquitous analytical technique for separating proteins based on molecular weight. Existing loading buffers used in SDS-PAGE and other protein analyses techniques have difficulty in effectively solubilizing and stabilizing hydrophobic or lipidated proteins, particularly membrane proteins. These proteins tend to aggregate or precipitate...

The ability to monitor spatiotemporal dynamics of neurotransmitter release is crucial for understanding the basis of brain function. The precise cognitive operations supported by the changes in cortical neuromodulatory activity have not been fully recognized, largely due to the limitations of current methods which have trade-offs between spatial, temporal,...

Cellular force is important in activities including migration, proliferation and differentiation, which are mediated by interactions between the cell and the ECM. Monitoring these interactions helps to understand how and when mechanical cues play a role in cellular events and underlying mechanisms. However, there are limitations in spatial and temporal...

Cells have developed various means for transporting molecules across membranes as well as cellular compartments separated by membranes. Channels and pores can be formed with different protein assemblies to enable the regulated passage of molecules in and out of cells, which has led to them being exploited as molecular sensors for characterizing biomolecules...

Dermatology and beauty product research and development and testing has been limited to animal testing, which in some countries has been banned. Because of increasing controversial issues surrounding animal testing of these dermatology or beauty products, there has been increasing interest in developing in-vivo like in-vitro models for skin research. ...

Radio Frequency (RF) coils transmit and receive RF signals in magnetic resonance imaging (MRI). Designing FR coils is a challenge because they often have to operate at multiple frequencies and it is difficult to enable them to resonate at multiple frequencies or switch their resonating frequencies. Positive-intrinsic-negative (PIN) diodes are commonly...

Molecular interactions are integral to virtually all biological processes including cell signaling, enzyme activity, protein functionality, and disease development. Understanding the kinetics of these interactions is crucial for providing detailed quantitative and mechanistic insights, at the molecular level, which are essential for advancements in...

Understanding the relationship between protein sequence-structure and binding dynamics is not well understood. Of particular interest is the ability to relate foldability and function of a protein and the ability to characterize how foldability and binding change based on mutations in the protein sequence. WW domains are one of the most abundant independently...

Histological whole slide image (WSI) processing techniques are critical for identifying and classifying tissues, particularly cancerous tissues. AI-aided methods for analyzing these WSIs have become increasingly important to enhance diagnostic precision and high throughput processing. However, WSIs have gigapixel resolution, leading to computational...