Wound healing, although complex, is a remarkably organized process involving hemostasis, inflammation, new tissue generation and remodeling. However, when wounds cover a large surface area, become infected, or occur in patients with impaired healing capacity, such as diabetics or the elderly, wound healing can be prolonged and result in chronic ulceration...

Glucose, oxygen, and extracellular pH are important components of human metabolic processes -- many diseases are associated with glucose transport and metabolic disorders including diabetes and cancer. Monitoring glucose and cell metabolism can provide invaluable information for understanding these diseases. There are many assays and sensors for glucose,...

Glucose and oxygen are important components of human metabolic processes -- many diseases are associated with glucose transport and metabolic disorders including diabetes and cancer. Monitoring glucose and cell metabolism can provide invaluable information for understanding these diseases. There are many assays and sensors for both glucose and oxygen,...

Biological pattern formation requires complex gene regulation networks and accurate cell-cell coordination. The reaction-diffusion (RD) based clock and wavefront model has been proposed as a mechanism involved in biological pattern formation of repeated and segmented structures. While RD driven pattern formation has been demonstrated in many systems,...

Accurate detection and diagnosis of infectious diseases is paramount to appropriate treatment and better outcomes. Despite tremendous efforts to advance new diagnostic techniques, there are still critical gaps in the healthcare system in quickly diagnosing and responding to infectious diseases. Current diagnostic technologies identify pathogens by detecting...

Laparoscopic surgery, also called minimally invasive surgery, has become popular for many reasons. These procedures require smaller incisions, which reduces the patient’s pain, requires less medication, and allows the patient to heal more quickly than procedures using traditional surgery. Hospital stays are shorter, allowing the patient to return...

Genetic circuit engineering has played an important role in many forms of synthetic biology. Based on a large collection of well characterized biological components, complex gene circuits with designed functions can be wired using established biological principles. Currently circuit assembly has two main strategies: one is monocistronic construct, in...